Intan Technologies, LLC: low-noise amplifier microchips for electrophysiology, EKG, EMG, EEG, ECoG, and neural recording headstages and bio instrumentation

RHD2000 evaluation system
RHD2000 Evaluation System: RHD2000 USB interface board shown with 32-channel amplifier board with SPI interface cable. Up to four amplifier boards may be connected to the USB interface board. (Click for larger image.)

Main Documentation:

RHD2000 evaluation system user guide

RHD2000 recording system catalog

Supporting Documents:

RHD2000 USB/FPGA interface: Rhythm webpage, datasheet

SPI interface cable/connector specification

Application note: Data file formats

Application note: I/O voltage level shifting

Application note: Adapting SPI cables to a commutator

Application note: Accelerometer calibration for amplifier / accelerometer boards

Application note: Adding an LED to amplifier boards

Pricing information

RHD2164 64-channel amplifier board

RHD2164 amplifier board with 64 unipolar inputs

RHD2000 GUI interface screenshot
RHD2000 GUI interface screenshot (click for full-sized image)

Intan RHD2000 LabVIEW library
RHD2000 LabVIEW library: Sample Virtual Instrument designed using library

RHD2000-Series Amplifier Evaluation System

If you are new to Intan, please start with this brief Introduction to the RHD2000 System.

The RHD2000 Evaluation System is a modular family of open-source hardware and software that allows users to record biopotential signals from up to 256 low-noise amplifier channels using the revolutionary new RHD2000 series of digital electrophysiology chips from Intan Technologies.

A USB interface board connects to a host computer via a standard USB cable. Small amplifier boards connect to the interface board via thin, flexible all-digital cables that may be daisy-chained to form robust connections up to 10 meters in length. Open-source, multi-platform GUI software controls the operation of the amplifiers and streams data to the screen and to disk in real time at user-selected sampling rates from 1 kS/s to 30 kS/s.

The RHD2000 Evaluation System allows users to perform the following functions:

  • Monitor and record live signals from 16 to 256 low-noise amplifier channels using RHD2000 biopotential amplifier chips.
  • Reconfigure amplifier bandwidths and sampling rates from software.
  • Measure in situ electrode impedances (both magnitude and phase) at arbitrary frequencies with the click of a button.
  • Use eight on-board digital-to-analog converters (DACs) to reconstruct analog waveforms from selected amplifier channels with <1 ms latency.
  • Monitor audio of any two amplifier signals using a stereo "line out" jack.
  • Record up to eight auxiliary analog inputs and 16 digital inputs synchronized with amplifier data.

A complete evaluation system consists of a USB interface board, an SPI interface cable, and a small amplifier board. The USB interface board can support up to four amplifier boards. Each amplifier board contains an RHD2000 series amplifier chip with 16, 32, 64, or 128 channels. The amplifier board is connected to the USB interface board with a thin, flexible SPI interface cable. Multiple cables may be daisy-chained to form robust digital data links up to 10 meters in length.

There are seven types of amplifier boards available:

Bandwidths of all RHD2000 amplifier boards are software reconfigurable over a wide range from 0.1 Hz to 20 kHz.

If electrodes with the proper mating connectors are not available, Intan offers an electrode adapter board and two types of wire adapters for custom connections. An SPI cable adapter board allows the system to be used with commutators or other cables.

A dual headstage adapter allows two amplifier boards to be used with a single SPI interface cable.

The operation of the USB interface board and amplifier boards are described in more detail in the RHD2000 evaluation system datasheet. All components of the system are shown in the RHD2000 recording system catalog. The evaluation system is built around our open-source Rhythm USB/FPGA interface.

Complete schematics of the USB interface board and amplifier boards are available on our downloads page. Technical specifications for the SPI interface cables and connectors are available here.


Open-Source RHD2000 Interface Software

Before attaching the RHD2000 USB interface board to a computer, please first install these drivers. (You do not need to install the drivers to run the interface software in demonstration mode.)

Here is the complied RHD2000 interface software version 1.5.2 for Windows and Mac (updated 25 July2017). This software can be run with no evaluation system hardware or drivers present; it will generate synthetic neural or ECG data for demonstration purposes if no USB interface board is connected.

After recording data with this software, these m-file functions can be used to load the data files into MATLAB. This Python script can be used to load data files. We also provide a detailed description of data file formats and Windows command line software to convert Intan data files into Spike2 format.

Complete C++/Qt source code for the RHD2000 interface is available on our downloads page.


RHD2000 LabVIEW Library

An Intan LabVIEW library is available that links the RHD2000 USB evaluation system to the popular LabVIEW instrument control software from National Instruments. More information on this product as well as a trial license download may be found here.


RHD2000 MATLAB Toolbox

An Intan MATLAB Toolbox is available that links the RHD2000 USB evaluation system to the powerful MATLAB programming language from Mathworks. More information on this product as well as a trial license download may be found here.

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