Intan Technologies, LLC: low-noise amplifier microchips for electrophysiology, EKG, EMG, EEG, ECoG, and neural recording headstages and bio instrumentation

Example signals acquired with RHD2000 chips


Here are some real electrophysiological signals obtained using RHD2000 series digital electrophysiology interface chips and standard electrodes: electrocardiograms (ECG/EKG), electromyograms (EMG), and neural signals.

ECG from RHD2000 chip

ECG/EKG signal recorded with RHD2216 chip using Ag/AgCl electrodes on the chest. The amplifiers were configured with a lower cutoff frequency of 0.6 Hz and an upper cutoff frequency of 100 Hz. ADC sampling rate was 2 kS/s per channel.


EMG from RHD2000 chip

EMG signal recorded with RHD2216 chip using Ag/AgCl electrodes over bicep during two brief muscle contractions. The amplifiers were configured with a lower cutoff frequency of 10 Hz and an upper cutoff frequency of 1 kHz. ADC sampling rate was 4 kS/s per channel.


neural spikes and LFPs from RHD2000 chip

Neural action potentials (spikes) and local field potentials (LFPs) recorded with RHD2132 chip in SI/barrel cortex of a freely behaving mouse using a gold-plated nichrome tetrode. The amplifiers were configured with a lower cutoff frequency of 1 Hz and an upper cutoff frequency of 9.0 kHz. ADC sampling rate was 30 kS/s per channel. (Data courtesy of Jakob Voigts at MIT, Brown University, and open-ephys.org).


neural spikes from RHD2000 chip

The neural data from above acquired with an RHD2132 chip, high-pass filtered at 300 Hz in software to remove LFPs and isolate spikes. This filtering also could have been performed using the on-chip DSP high-pass filter.


time-aligned neural spikes from RHD2000 chip

Several time-aligned cortical spikes from the data shown above acquired with an RHD2132 chip. The time axis has been expanded to show the precise shape of each spike over a 1 ms window.


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