RHA Electrophysiology Amplifier Chips

Introduced in 2010, RHA2000 amplifier chips are low-power microchips that contain 16 or 32 low-noise amplifiers for electrophysiology monitoring and recording applications. RHA2000 series chips are available in standard QFN surface-mount packages for solder assembly on printed circuit boards.

The RHA2000 chips have multiplexed analog outputs, so an external ADC must be added. Our newer RHD2000 amplifier chips, introduced in 2012, incorporate an on-chip ADC as well as additional functionality and are recommended for new designs.

RHA2000 Family

  • RHA2116 16-channel amplifier chip with unipolar inputs and common reference
  • RHA2216 16-channel amplifier chip with bipolar (differential) inputs
  • RHA2132 32-channel amplifier chip with unipolar inputs and common reference

Features

  • Fully integrated electrophysiology amplifiers; no off-chip filter capacitors required
  • On-chip analog multiplexer allows many amplifiers to share one external ADC
  • Low noise floor: 2 μV rms typical
  • Upper cutoff frequency set by external resistor; configurable from 10 Hz to 20 kHz
  • Lower cutoff frequency set by external resistor; configurable from 0.02 Hz to 1000 Hz
  • In situ electrode impedance measurement capability with additional external components

Applications

  • Miniaturized multi-channel headstages for neural recording
  • Low-power wireless headstages or backpacks for electrophysiology experiments
  • "Smart Petri dish" in vitro recording systems
  • Simultaneous recording of action potentials and local field potentials (LFPs) from microelectrodes